Sickle Cell Anemia: Reference Values of Cerebral Blood Flow Determined by Continuous Arterial Spin Labeling MRI
نویسندگان
چکیده
منابع مشابه
Cerebral blood flow measurement in children with sickle cell disease using continuous arterial spin labeling at 3.0-Tesla MRI.
BACKGROUND AND PURPOSE Cerebral infarction is an important complication of sickle cell disease (SCD) and occurs in one third of the patients with SCD. The risk of infarction is commonly attributed to the hyperemia that is associated with anemia and reduces the cerebral vascular reserve. We measured regional cerebral blood flow (rCBF) by continuous arterial spin labeling MRI, which is a noninvas...
متن کاملInverse correlation between cerebral blood flow measured by continuous arterial spin-labeling (CASL) MRI and neurocognitive function in children with sickle cell anemia (SCA).
Overt stroke, clinically "silent" cerebral infarct, and neurocognitive impairment are frequent complications of sickle cell anemia (SCA). Current imaging techniques have limited sensitivity and specificity to identify children at risk for neurocognitive impairment. We prospectively evaluated 24 children with SCA with a neurologic exam, complete blood count, transcranial Doppler ultrasound (TCD)...
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Non-invasive measurement of Cerebral Blood Flow (CBF) is now feasible thanks to the introduction of Arterial Spin Labeling (ASL) Magnetic Resonance Imaging (MRI) techniques. To date, the low signalto-noise ratio of ASL gives us no option but to repeat the acquisition in order to accumulate enough data to get a reliable signal. Perfusion signal is usually extracted by averaging across the repeti...
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Arterial spin labeling (ASL) techniques are gaining popularity for visualizing and quantifying cerebral blood flow (CBF) in a range of patient groups. However, most ASL methods lack vessel-selective information, which is important for the assessment of collateral flow and the arterial supply to lesions. In this study, we explored the use of vessel-encoded pseudocontinuous ASL (VEPCASL) with mul...
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Introduction Cerebral perfusion imaging plays an important role in the evaluation of brain disease. Arterial spin labeling (ASL) is a relatively new and non-invasive perfusion imaging technique that uses magnetically labeled arterial blood water protons as an endogenous tracer of flow. Its non-invasiveness makes ASL an attractive tool compared to standard clinical methods. However, low SNR and ...
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ژورنال
عنوان ژورنال: The Neuroradiology Journal
سال: 2013
ISSN: 1971-4009,2385-1996
DOI: 10.1177/197140091302600209